Impact of glutathione S-transferases (GSTs) in insect resistance in the citrus mealybug (Pseudococcus viridis)

This study investigated the biological role of glutathione S-transferases (GSTs) in inducing insect resistance in Pseudococcus viridis, a major pathogen in citrus agriculture. These high levels of GST indicate an adaptive detoxification mechanism that allows P. viridis to survive despite repeated applications of insecticides. The findings highlight GSTs as important enzymes in disease resistance pathways, supporting their potential as targets for integrated pest management (IPM). Interestingly, Inhibition of GST can impair detoxification pathways, thereby restoring pesticide efficacy and providing sustainable antimicrobial actions in citrus production has increased.